USA Today published last week (alas, I can't find it online any longer) a general interest article on the future of string theory since, so far, little real world data has been brought to bear in support of the idea. In the article, Lee Smoling, the author of The Trouble with Physics: The Rise of String Theory, the Fall of Science, and What Comes Next, believes that crucial evidence is missing and experimentation is next to impossible.
String theory, which suggests a universe of ten or more dimensions, offers a potential grand solution, a theory of everything uniting general relativity, which explains the contours of space and time, and quantum mechanics, which describes the machinery of inner space, of the tiniest matter.
In addition to the obvious question - does the theory, in fact, correspond with reality? - the article highlights the differences between the two historic methods of knowing - rationalism and empiricism. If I may summarize: Smoling wants us to know that science is reason + evidence.