Whence "breakthrough innovation?" Steve Hardy at Creative Generalist believes that breakthrough ideas, which he distinguishes from innovation, come from "the confluence of disciplines." Like Steve, I believe generalism as a perspective offers a method for exploring the space -- the ideas -- between disciplines. Innovation is to ideas what technology is to science -- it's the conceptual grounding that matters.
How can generalism be taught? With its emphasis on modeling, abstraction and dimensional thinking, design, I believe, offers one method for training the generalist mind. It also corresponds closely with how humans create, which often involves a pre-verbal intuition, the truth of which is later brought forward with logic and reason.
My two cents.